Fish gotta swim, birds gotta fly, and squids gotta jet away from predators rapidly. All cephalopods (squid, cuttlefish, octopus, etc.) are squishy, soft-bodied animals; basically swimming food to anything that can catch them. As an evolutionary consequence, all members of this class of animals evolved a number of remarkable defensive strategies. Their camouflaging abilities are some of the most intellectually and aesthetically captivating behaviors in the contemporary animal world. The ink defense of some species of squid is likewise famous and makes inglorious appearances in popular movies and television, such as Finding Nemo and Futurama. And most people know that when they need to, squid can jet through the water at remarkable speeds, by some estimates up to twenty miles per hour.
Squid jet away from predators by sucking water into their mantle (the main part of their body), and then squeezing the mantle while allowing the water to exit in only one direction. As defense mechanisms go it’s a good one, but it has to be executed quickly and powerfully, which is no small physiological task. In order to accomplish the task, members of the Loligo genus of squid have long cable-like motor neurons which run from a specialized nerve bundle, called a ganglion, to the muscles in their mantle. These motor neurons, called the squid giant axon, were discovered by John Zachary Young, and rather by accident. Young was a charismatic and eclectic researcher. And in the early 1930’s he was traveling to many different labs in the UK, throughout Europe, and in the US.
- Biophysical Association. 2016. Kenneth S. Cole Award. http://www.biophysics.org.
- Boycott, Brian. 1998. "John Zachary Young. 18 March 1907-4 July 1997." Biographical Memoirs of Fellows of the Royal Society, November: 486-509.
- Cole, Kenneth. 1949. "Dynamic electrical characteristics of the squid axon membrane." Archives des Sciences Physiologiques 3: 253-258.
- Cole, Kenneth. 1965. "Electrodiffusion models for the membrane of squid giant axon." Physiological review 45: 340-379.
- Cole, Kenneth. 1941. "Rectification and inductance in the squid giant axon." Journal of General Physiology 25: 29-51.
- Cole, Kenneth, and H.J. Curtis. 1938. "Electric impedance of th4e squid giant axon during activity." Journal of General Physiology 22: 649-670.
- Gilbert, Daniel, William Adelman, and John Arnold. 1990. Squid as Experimental Animals. New York , NY: Plenum Press.
- Hodgekin, Alan, and B. Katz. 1949. "The effect of sodium ions on the electrical activity of the giant axon of the squid." Jouranl of physiology 108: 37-77.
- Hodgkin, Alan Lloyd. 1963. "The inoic basis of nervous conduction." Nobel Lecture.
- Hodgkin, Alan. 1963. "The ionic basis of nervous conduction." Nobel Lecture, December 11.
- Hodgkin, Alan, and Andrew Huxley. 1939. "Action potentionals recorded from insdide of a nerve fibre." Nature 144: 710-711.
- Hodgkin, Alan, and Andrew Huxley. 1947. "Potassium leakage from an active nerve fiber." Journal of Physiology 106: 341-367.
- Huxley, Andrew F. 1963. "The quantitative analyisis of excitation and conduction in nerve." Nobel Lecture.
- Huxley, Andrew. 2002. "From overshoot to voltage clamp." TRENDS in Neuroscience 25 (11): 553-558.
- —. 1996. "Kenneth Stewart Cole: July 10, 1900–April 18, 1984." National Academy of Sciences Biographical Memoir.
- —. 1963. "The quantitative analysis of excitation and conduction in nerve." Nobel Lecture, December 11.
- Keynes, Richard. 1999. "John Zachary Young (18 March 1907-4 July 1997)." Proceedings of the American Philosophical Society, December: 728-732.
- Nobelprize.org. 2016. "The Nobel Prize in Physiology or Medicine 1963." Nobel Media.
- Piccolino, Marco. 2002. "Fifty years of the Hodgekin-Huxley era." TRENDS in Neuroscience 25 (11).
- Schwiening, Christof J. 2012. "A brief historical perspective: Hodgkin and Huxley." Journal of Physiology 2571-2575.