Working on Fundulus eggs and embryos allowed Trinkaus to have a long, successful research career at Yale, which enabled him to make many discoveries that contributed to the understanding of the complex cell movements during gastrulation (see Chapter 6), but the process of choosing any experimental subject can also constrain a scientist’s research prospects. During the early 1980s, Trinkaus went to France to conduct research at the famous Station Biologique de Roscoff, and observed the development of another teleost fish, Blennius pholis. Trinkaus was able to make a novel discovery about directional cell movements because of a slight difference in the behaviour of pigment cells, or melanocytes, in Blennius and Fundulus.
While both Blennius and Fundulus have melanocytes in their yolk sacs, the pigmented cells in Blennius behave differently than those in Fundulus. Trinkaus’s attention to detail allowed him to notice those peculiar patterns and devise experiments to test hypotheses about the behaviour and movement of Blennius’ melanocytes. From these experiments, he published two papers in the Journal of Experimental Zoology in 1988 (Trinkaus 1988a; 1988b). Trinkaus thus remarked: “a little tinkering with other material from time-to-time can be both refreshing and scientifically revealing…in any case, the guiding principle for serious research should always be the problem or concept involved, not the organism” (Trinkaus 2003, 259).
- Atz, James W. "Fundulus heteroclitus in the laboratory: a history." American zoologist 26, no. 1 (1986): 111-120.
- Betchaku, Teiichi, and J. P. Trinkaus. “Programmed endocytosis during epiboly of Fundulus heteroclitus.” American zoologist 26, no. 1 (1986): 193-199.
- Davis, Edward M., and J. P. Trinkaus. "Significance of cell-to-cell contacts for the directional movement of neural crest cells within a hydrated collagen lattice." Journal of embryology and experimental morphology 63, no. 1 (1981): 29-51.
- DuPont, Ellen M. "John Philip Trinkaus (1918-2003)." Embryo Project Encyclopedia (2012).
- Goodrich, H. B., and J. P. Trinkaus. "The differential effect of radiations on mendelian phenotypes of the goldfish, Carassius auratus." The Biological Bulletin 77, no. 2 (1939): 192-199.
- Goodrich, H. B., and J. P. Trinkaus. "The differential effect of radiations on mendelian phenotypes of the goldfish, Carassius auratus." The Biological Bulletin 77, no. 2 (1939): 192-199.
- Goodrich, H. B., N. D. Josephson, J. P. Trinkaus, and Jeanne M. Slate. "The cellular expression and genetics of two new genes in Lebistes reticulatus." Genetics 29, no. 6 (1944): 584-592.
- Keller, Ray, Wallis H. Clark, and Frederick Griffin (Eds.) Gastrulation: Movements, Patterns, and Molecules. New York: Plenum Press, 1991.
- Kimmel, Charles B., and James A. Weston. "An overview of Trink's scientific accomplishments." Developmental Dynamics 228, no. 4 (2003): 586-587.
- Saunders, John W. "Trink, the man." Developmental Dynamics 228, no. 4 (2003): 588-590
- Schoenwolf, Gary C. "Trink: His life, his philosophy." Developmental Dynamics 228, no. 4 (2003): 591-593.
- Tickle, Cheryll A., and J. P. Trinkaus. "Change in surface extensibility of Fundulus deep cells during early development." Journal of cell science 13, no. 3 (1973): 721-726.
- Tickle, Cheryll A, and J. P. Trinkaus. "Observations on nudging cells in culture." Nature 261, no. 5559 (1976): 413-413.
- Trinkaus, J. Philip. "Factors concerned in the response of melanoblasts to estrogen in the Brown Leghorn fowl." Journal of Experimental Zoology 109, no. 1 (1948): 135-169.
- Trinkaus, John Philip. "The surface gel layer of Fundulus eggs in relation to epiboly." Proceedings of the National Academy of Sciences of the United States of America 35, no. 4 (1949): 218.
- Trinkaus, John Philip. "A study of the mechanism of epiboly in the egg of Fundulus heteroclitus." Journal of Experimental Zoology 118, no. 2 (1951): 269-319.
- Trinkaus, John Philip. "The differentiation of tissue cells." American Naturalist (1956): 273-289.
- Trinkaus, John Philip. “Procurement, maintenance and use of Fundulus eggs,” Methods in Developmental Biology. F.H. Wells and N.K. Wessells (Eds.) Crowell, New York: 1967, 113-122.
- Trinkaus, J. P. "The cellular basis of Fundulus epiboly. Adhesivity of blastula and gastrula cells in culture." Developmental biology 7 (1963): 513-532.
- Trinkaus, J. P. "Surface activity and locomotion of Fundulus deep cells during blastula and gastrula stages." Developmental biology 30, no. 1 (1973): 68-103.
- Trinkaus, J. P. "Mechanism of Fundulus epiboly—a current view." America n Zoologist 24, no. 3 (1984): 673-688.
- Trinkaus, John Philip. Cells into organs: the forces that shape the embryo. (2nd Ed.) New Jersey: Prentice-Hall, Inc., 1984.
- Trinkaus, John Philip. “Directional cell movement during early development of the teleost Blennius Pholis. I. Formation of epithelial cell clusters and their pattern and mechanism of movement.” Journal of Experimental Zoology 245 (1988a): 157-186.
- Trinkaus, John Philip. “Directional cell movement during early development of the teleost Blennius Pholis. II. Transformation of the cells of epithelial clusters into dendritic melanocytes, their dissociation from each other, and their migration to and invasion of the pectoral fin buds.” Journal of Experimental Zoology 248 (1988b): 55-72.
- Trinkaus, John Philip. Embryologist: My Eight Decades in Developmental Biology. J&S Publishing Company, 2003
