John Philip Trinkaus - New Location & New Research Problem

After Trinkaus finished his doctoral project and had secured a junior position at Yale, he began to explore other avenues of research in embryology, knowing that he wanted to move away from problems on the specificity of induction of pigmentation patterns in chickens. To delineate a new research program for his future career at Yale, Trinkaus spent the end of his graduate career re-reading major works in embryology, including Hans Spemann’s Embryonic Development and Induction, Paul Weiss’s Principles of Development, and Johannes Holtfreter’s Tissue Affinity, A Means of Embryonic Morphogenesis and A Study of the Mechanism of Gastrulation. It was the latter works by Holtfreter that inspired Trinkaus to study gastrulation and the mechanism of epiboly.